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      Tag: is migraine curable

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      American Nutrition Association conference in San Diego, November 2019

      Happy Announcement

      I am slowly moving migraine as a metabolic disease in front of as many scientists as possible. As some of you know, I was elected to become a member of the American College of Nutrition (ACN) last year and finished their keto training course under the American Nutrition Association (ANA), which is a member of (or part of) the ACN. They have a conference coming up in November in San Diego, my neck of the woods, so I applied and got accepted into the poster session. This is the first nutrition-based academic organization where I present a poster on migraine, so it is exciting!
       
      If you will be part of this conference, let me know! It would be great to meet. It is an academic conference, so it is not free to enter.
       
      Because it is in a session on From Chronic Disease to Regeneration by Nutrition, the title of my submission contains the the session title.
       
      Here is what was accepted:

      Migraine: From Chronic Disease to Regeneration by Nutrition

      Abstract:
      Migraines are misunderstood by scientists and physicians. Migraines are either considered to be vascular disease(1), neurological disease(2), the combination of to two(3) or “mental disease”(4). Research also suggests that migraineurs may suffer from metabolic syndrome(5). Migraine is a form of channelopathy, where the brain places ionic and metabolic limitation on what a migraineur can safely eat without generating a migraine. Migraine is genetic and is defined by the following states: hyper-sensory brain(6); increased neuronal connections(7); extra voltage used by extra connections(8,9); channelopathy(10); glucose entering cells causes sodium efflux(11); migraine brain uses more sodium(12); kidney increase sodium by wasting potassium(13,14) and water; the renal system increases blood pressure(15); the reduced amount of sodium in circulation triggers increased production of aldosterone, cortisol, and adrenaline(16); cortisol and adrenaline increase glucose in the blood(17); when glucose enters the cells, sodium and water leave the cell, reducing sodium, which initiates the previous steps with adrenaline and cortisol11. This catch 22 cycle builds up to electrolyte imbalance, starting migraine. In this presentation, I hope to connect these disparate dots to form a coherent picture of migraine is and show how the proper nutrition may prevent migraines.
      1 Schottstaedt, W. W. & Wolff, H. G. Studies on headache: Variations in fluid and electrolyte excretion in association with vascular headache of migraine type. A.M.A. Archives of Neurology & Psychiatry 73, 158-164, doi:10.1001/archneurpsyc.1955.02330080036011 (1955).
      2 Lipton, R. B. & Pan, J. Is migraine a progressive brain disease? JAMA 291, 493-494, doi:10.1001/jama.291.4.493 (2004).
      3 Fabjan, A., Zaletel, M., #x17d & van, B. Is There a Persistent Dysfunction of Neurovascular Coupling in Migraine? BioMed Research International 2015, 11, doi:10.1155/2015/574186 (2015).
      4 Antonaci, F. et al. Migraine and psychiatric comorbidity: a review of clinical findings. The Journal of Headache and Pain 12, 115-125, doi:10.1007/s10194-010-0282-4 (2011).
      5 Guldiken, B. et al. Migraine in Metabolic Syndrome. The Neurologist 15, 55-58, doi:10.1097/NRL.0b013e31817781b6 (2009).
      6 Schwedt, T. J. Multisensory Integration in Migraine. Curr Opin Neurol, 248-253 (2013).
      7 Tso, A. R., Trujillo, A., Guo, C. C., Goadsby, P. J. & Seeley, W. W. The anterior insula shows heightened interictal intrinsic connectivity in migraine without aura. Neurology, 1043-1050 (2015).
      8 Liu, H. et al. Resting state brain activity in patients with migraine: a magnetoencephalography study. The Journal of Headache and Pain 16, 42, doi:10.1186/s10194-015-0525-5 (2015).
      9 Xue, T. et al. Intrinsic Brain Network Abnormalities in Migraines without Aura Revealed in Resting-State fMRI. PLOS ONE, e52927 (2012).
      10 Albury, C. L., Stuart, S., Haupt, L. M. & Griffiths, L. R. Ion channelopathies and migraine pathogenesis. Molecular Genetics and Genomics 292, 729-739, doi:10.1007/s00438-017-1317-1 (2017).
      11 Longo, D. L. et al. Harrison’s Manual of Medicine 18th Edition. (McGraw Hill Medical, 2013).
      12 Campbell, D. A., Tonks, E. M. & Hay, K. M. An Investigation of the Salt and Water Balance in Migraine. British Medical Journal, 1424-1429 (1951).
      13 Huang, C.-L. & Kuo, E. Mechanism of Hypokalemia in Magnesium Deficiency. Journal of the American Society of Nephrology 18, 2649-2652, doi:10.1681/asn.2007070792 (2007).
      14 Muto, S., Asano, Y., Okazaki, H. & Kano, S. Renal Potassium Wasting in Distal Renal Tubular Acidosis : Role of Aldosterone. Internal Medicine 31, 1047-1051, doi:10.2169/internalmedicine.31.1047 (1992).
      15 Sharma, R. S., Sandeep;. in Physiology, Blood Volume (StatPearls Publishing, 2018).
      16 Goldstein, D. S. Adrenal responses to stress. Cellular and molecular neurobiology 30, 1433-1440, doi:10.1007/s10571-010-9606-9 (2010).
      17 Pernet, A. W., M; Gill, GV; Orskov, H; Alberti, KG; Johnston, DG;. Metabolic effects of adrenaline and noradrenaline in man: Studies with somatostatin. Diabetes Metabolism; 10, 7 (1984).
      September 24, 2019
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      News
      An important message from a migraine sufferer

      This message is from a neuropsychologist who was forced into retirement early due to migraines, and who is in the Facebook migraine group.

      “I’ve always had inexplicable physical (and emotional) symptoms that I knew were brain based. Simply put, my brain has been starving for most of my life. Dr. Stanton’s incredible ability to pull together many disparate fields of study–biochemistry, nutrition, neurobiology–into a sensible, simple theory of migraine has transformed my life. Not only do I not crave or desire carbohydrates, I see them as poison. I have much more empathy for myself and can finally stop worrying, stop hating myself, and start healing. I’ve only been officially associated with the protocol for three days and I already have seen an enormous reduction in migraine head pain. It almost feels like a thing of the past and I can’t imagine sabotaging myself now that I have hope and insight. Knowledge is key. No longer will I have to frantically go down rabbit holes chasing the latest incorrect, fad theory of diet and migraine. I don’t have to fear food and its purported allergens any longer. I know exactly what my brain needs. Now I can give credence to my formerly mysterious bodily symptoms (rather than ignoring them) and take action to help myself in the moment. Better health can be had by anyone who wants it. Just had to get that out. Ok. Breathe.”

      You can also find this post at the Stanton Migraine Protocol’s testimonials website.

      Please contact us for more information.

      April 24, 2019
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